Azizi, S., R. Kheirandish, M. M. Oloumi & N. Nadimi, 2017.

Histopathologic findings in multicentric placental chorangioma with trophoblastic proliferation in a sheep.

Bulg. J. Vet. Med., 20, No 4, 400–407.   DOI: 10.15547/bjvm.994

The present study described chorangioma in a sheep with clinical signs of dystocia. During surgery, foetus was not found and both of the uterine horns were distended with a lot of liquid. Multiple well-demarcated nodules of firm consistency, yellow-tan colour and 2.5–4 cm diameter were projected from the cotyledons into the lumens. Histopathologically, the nodules showed expanded chorionic villi composed of proliferated blood vessels in a variable amount of loose perivascular stroma. Syncytial trophoblast cells with hyperchromatic nucleus were dispersed in the tumour’s  parenchyma. Based on pathologic characteristics and according to the abundant vascular proliferation and nodular form, a neoplastic lesion named chorangioma was diagnosed. To the author’s knowledge, it is the first report of chorangioma in sheep.

Key words: chorangioma, histopathology,  sheep