Hashemnia, M. & z. Nikousefat, 2017.

Primary lung squamous cell carcinoma in a lary breed cock (gallus gallus domesticus) with multiple skin metastases.

Bulg. J. Vet. Med., 20, No 4, 392–399.   DOI: 10.15547/bjvm.988

The present study describes for the first time a case of primary lung squamous cell carcinoma with multiple skin metastases in a 7-year-old Lary breed cock. On physical examination, multiple, firm, mobile, ulcerative nodules, 3 to 4 cm in diameter were observed on the neck. Atypical squamous cells were observed in the skin fine needle aspiration. Histopathologically, variably sized masses of concentrically arranged neoplastic squamous epithelial cells with the horn pearl formation were observed in the dermis. At necropsy, the lung was consolidated and had multifocal tan masses containing a tenacious exudate. Similar nodules were observed in the liver. On the histopathological sections, the lung and liver contained large multifocal areas of necrosis intermixed with cords, sheets, and nests of round to oval neoplastic cells. The presence of keratin material was common in the center of neoplastic cells islands as keratin pearls. Given the morphologic features of the neoplasm, a diagnosis of primary lung squamous cell carcinoma was made. Although the incidence of primary lung SCC is likely too low in the birds, but it should be considered in the differential diagnosis.

Key words: cock, lung squamous cell carcinoma, skin metastasis