Bulgarian Journal of Veterinary Medicine (BJVM)
ISSN 1311-1477
Bulgarian Journal of Veterinary Medicine
VOL. 7, No 4, DECEMBER, 2004
CONTENTS
197
FULL TEXTA. R. Burriel, I. Tsachev & S. B. Ramantanis
Is Mycobacterium avium subsp paratuberculosis (Map) a potential food-borne zoonotic agent?209
FULL TEXTB. Aminkov & V. Manov
Electrochemotherapy – a novel method of treatment of malignant tumours in the dog215
FULL TEXTk. kalinova
Treatment of Complicated Forms of Liver Hydatidosis223
FULL TEXTM. P. Popova & N. S. Nikolova
Influence of Agriya 1050 on blood parametеrs in lambs229
FULL TEXTT. K. Stoyanchev, N. A. Bozakova, D. J. Yarkov,
K. T. Stoyanchev, I. T. Yotova, M. G. Oblakova
& M. T. Lalev
Study on the productivity of turkey-broilers, bred on different floor types235
FULL TEXTG. M. Sarov, G. S. Ilieva & T. I. Vlaykova
A case with unusual blood chemistry parameters following a glucose tolerance test and stress
(no summary is available)239
FULL TEXTt. todorov
A preclinical study on Biofloxavet C (enrofloxacin) tolerance in cats
(no summary is available)245
FULL TEXTI. Borissov, D. Sivrev & N. Milev
Incidence of some teeth and occlusion abnormalities in dogs: a retrospective study (1995-2002)
(no summary is available)Published by the Trakia University, Faculty of Veterinary Medicine,
6000 Stara Zagora, Bulgaria
Volume 7, Number 4, December 2004, Summaries
Burriel, A. R., I. Tsachev & S. B. Ramantanis, 2004. Is Mycobacterium avium subsp. paratuberculosis (Map) a potential food-borne zoonotic agent? Bulg. J. Vet. Med., 7, No 4, 197-208.
The spreading of Mycobacterium avium (Map) infections among animals is a representative example of an on-going evolution of microbes in the environment. However, is it or could it be a potential zoonotic agent? If it is proven as such, then how men are infected? What is the route of transmission? To this date there is only speculation on these questions. Crohn’s disease in men resembles clinically and histopathologically Johne’s disease in animals, and Map has been isolated from both, but it has yet to be proven as cause of clinical disease in humans. Regardless of the eventual outcome of on going research, food scientists should remember that the possible sources of infection of men with Map are feces from infected animals or men, containing large numbers of this microorganism, and food contaminated accidentally or by excretion from infected animals. Specifically, milk from infected animals is the most likely source, if pasteurization fails to kill the microorganism. Time, temperature of pasteurization and the number of microorganisms are critical for the effectiveness of pasteurization. Failing of pasteurization has been observed even with the high temperatures of ultra pasteurization, if bacterial numbers are high.
Key words: Crohn's disease, Johne’s disease, Mycobacterium avium, paratuberculosis
Aminkov, B. & V. Manov, 2004. Electrochemotherapy – a novel method of treatment of malignant tumours in the dog. Bulg. J. Vet. Med., 7, No 4, 209-213.
The aim of the study was to assess the efficacy of electrochemotherapy for treatment of malignant tumours in dogs. The method comprised the local injection of a cytotoxic drug and the application of powerful electrical impulses causing increased permeability of cellular membrane. Thus, the antitumour agent could permeate the cell and exert its toxic effect.
The study was performed in 4 dogs with the following neoplasms: a Dogue with mammary adenocarcinoma, a Boxer and a German Shepherd, both with epulis and a Poodle with a squamous cell carcinoma of the lower lip.
A single injection of bleomycin (1.5–3 mg/cm3) was applied into the neoplastic growth. Ten 10 min later, 8 biphasic impulses with a duration of 50 ms and intensity of 1300 V/cm2 (for cutaneous neoplasms) and 800 V/cm2 (for mucosal lesions) were applied. The electrodes were two parallel steel calipers with a diameter of 0.8 mm and length of 14 mm. The distance between electrodes was 5–30 mm.
In all patients, the treatment resulted in a positive effect with gradual regression and disappearance of the tumour formation.
Key words: bleomycin, dog, electrochemotherapy, malignant tumours
Kalinova, K., 2004. Treatment of complicated forms of liver hydatidosis. Bulg. J. Vet. Med., 7, No 4, 215-221.
Hydatidosis is a widespread zoonosis infecting a large number of animals and humans. Surgical operations and therapeutic approaches were studied and analysed in 21 patients (14 female and 7 male) at the age of 14-78 that presented cases of confirmed liver hydatidosis with the following complications: 6 cases of cyst suppurations, 5 cases with cystic perforations, 3 cases with mechanical icterus and 7 cases of recurrences. In cyst suppurations echinococcectomy was performed with drainage of the residual cavity in 4 patients. In the patients with cystic perforation, 3 echinococcectomies with cholecystectomies and biliary tract explorations (cases of intrabiliary ruptures) and 2 echinococcectomies with lavage and drainage of the abdominal cavity (cases of direct rupture) were performed. In 2 cases of icterus, echinococcectomy with cholecystectomy and internal derivation of the "choledochoduodenoanstomosis" type was made and in 1 case - Kerh drainage. The 7 patients with recurrences were submitted to atypical liver resections in 3 and echinococcectomies in 4 cases respectively. The average postoperative stay was 11 days (7-28 days). The mean follow-up time was 60 months (6-120 months). The choice of the operative approach should be based on the experience of the surgeon and topic characteristic.
Key words: complications, liver hydatidosis, surgical treatment
Popova, M. P. & N. S. Nikolova, 2004. Influence of Agriya 1050 on blood parametеrs in lambs. Bulg. J. Vet. Med., 7, No 4, 223-228.
The study aimed to observe in dynamics the influence of the organophosphorus preparation Agriya 1050 containing fenitrothion as active substance [O,O-dimethyl O-(3-methyl-4-nitrophenyl) phosphorothioate], applied at various doses and durations of treatment on some enzymatic and non-enzymatic blood indices in lambs.
The data showed that the acute intoxication (single oral dose of 150 mg/kg) with the insecticide did not result in an immediate response. The peak deviations in observed parameters occurred by post treatment day 6 and thereafter a normalization followed. The changes observed following repeated treatment (orally at 50 mg/kg four times at 7-day intervals) and their comparison to the acute experiment allowed us to summarize that the organism of lambs succeeded to become accustomed to challenge doses and duration with the organophosphorus preparation Agriya 1050, used in the present experiments.
Key words: ceruloplasmin, lambs, lipid peroxidation, total cholesterol, total lipids, total protein
Stoyanchev, T. K., N. A. Bozakova, D. J. Yarkov, K. T. Stoyanchev, I. T. Yotova, M. G. Oblakova & M. T. Lalev, 2004. Study on the productivity of turkey-broilers, bred on different floor types. Bulg. J. Vet. Med., 7, No 4, 229-233.
The experiments were performed on 80 turkey-broilers from 2 hybrid types (BUT-9 and StZ-1), allotted into 4 groups, raised on slat floor or on litter. The body weight and forage expenditure per 1 kg weight gain of birds was investigated from the hatching to the 112th day. In both hybrids, a higher average body weight was observed in birds raised on slat floor compared to those raised on litter. The forage expenditure per 1 kg weight gain was lower in turkey-broilers raised on slat floor.
Key words: body weight, forage expenditure, litter, slat floor, turkey-broilers, weight gain