Bulgarian Journal of Veterinary Medicine (BJVM)


ISSN 1311-1477

Bulgarian Journal of Veterinary Medicine
VOL. 6, No
1, MARCH, 2003

 

 CONTENTS

1

Vodenicharov, A. and S. Danchev
A comparative anatomical study of renal artery architechtonics in the wild pig (Sus scrofa scrofa) and the domestic pig (Sus scrofa domestica)

9

D. Dimitrov
Localization of sensory nerve endings in the tip of tongue in budgerigars (Melopsittacus undulatus) - a light microscopic study

17

Anguelov, A., L. Belchev, Ch. Christev and M. Chichovska
Comparative study on the ability of 2,3 dimer­captosuccinic acid and D-penicillaine to enhance urinary excretion of lead in rabbits

21

L. Lashev and A. Haritova
Pharmacokinetics of colistin in broiler chickens

27

I. Borissov, S. Tsanova, I. Panchev, Ph. Stanchev, K. Rachkova and M. Koleva
Efficacy of the preparation Dentisept in dogs with gingivites

35

Z. kirkova
Studies on the life cycle of Trichuris vulpis

43

A. ivanov and D. kanakov
First case of canine hepatozoonosis in Bulgaria
(
no summary is available)

47

R. Binev, P. Petkov and A. Rusenov
A case of intoxication with the anticoagulant rodenticide bromadiolone in a dog

(
no summary is available)

Published by the Trakia University, Faculty of Veterinary Medicine,
6000 Stara Zagora, Bulgaria

Volume 6, Number 1, March 2003, Summaries

Vodenicharov, A. and S. Danchev, 2003. Comparative anatomical study of renal artery architechtonics in the wild pig (Sus scrofa scrofa) and the domestic pig (Sus scrofa domestica). Bulg. J. Vet. Med., 6, No 1, 1-8.

The arising of renal arteries and the architectonics of extra- and intrarenal branches were studied in situ and on corrosion casts in the wild pig. It was found out that the kidneys of the wild pig are supplied with blood only via the right and the left renal artery, each one being divided at the hilus into cranial and caudal branches (A. renalis cranialis and A. renalis caudalis). In 65% of studied organs, the caudal renal artery was shown to vascularize the middle and the caudal thirds of the kidney while in the rest 35% both arteries were branched in the respective halves of the renal parenchyma. Prelobar arteries were observed, located primarily in the renal sinus. The architectonics of interlobar and arcuate arteries as well as of convoluted arteries in the renal sinus was described. The similarities and differences of renal arterial architectonics in the wild and domestic pig were outlined.

Key words: arteries, kidneys, wild pig

Dimitrov, D., 2003. Localization of sensory nerve endings in the tip of tongue in budgerigars (Melopsittacus undulatus) - a light microscopic study. Bulg. J. Vet. Med., 6, No 1, 9-15.

The aim of this light microscopic study was to detect the presence or absence of sensory nerve endings in the tip of the tongue in budgerigars, their type and localization. The study was performed in 6 sexually mature budgerigars (3 from each gender). Following anaesthesia, decapitation and dissection of tongue tips, enduring histological preparations were made using the classical methods. Few free sensory nerve endings were detected only among the dorsal epithelium of tongue tip, where their thickened ends reached as far as the granular sublayer.  The epithelium of the ventral tongue surface contained several, taste bud-like structures.  The study revealed the highest incidence of the lamelar type nerve endings. Herbst bodies with various size reached the end cellular receptors of complex secondary papillae in the tongue back, the smaller papillae from the lateral and ventral parts as well as the subpapillar regions. Bodies with a cylindrical shape but with a smaller size, similar to Herbst or Vater-Pachini  bodies were observed. Some Ruffini bodies were localized deeply among the connective tissue of the propria. Structures similar to Meissner bodies occupied the connective tissue papillae of both dorsal and lateral tongue surfaces. The results of the study suggested that sensory nerve endings were from a type, identical to generally known ones, but their localization in the tonggue tip of budgerigars was not similar to that in other avian species and was different from that in mammals.

Key words: budgerigar, nerve endings, tongue

Anguelov, A., L. Belchev, Ch. Christev and M. Chichovska, 2003. Comparative study on the ability of 2,3 dimercaptosuccinic acid and D-penicillamine to enhance urinary excretion of lead in rabbits. Bulg. J. Vet. Med., 6, No 1, 17-20.

The potential of 2,3 dimercaptosuccinic acid (DSMA) and D-penicillamine - heavy metal chelating drugs which enhance the urinary excretion of lead and restore altered levels of urinary δ-aminolevulinic acid (δ-ALA) and blood δ-aminolevulinic acid dehydratase (δ-ALA-D) in lead poisoned rabbits, was compared. The performance of DMSA was better than that of D-penicillamine. It was attributed to the two –SH groups as stronger metal binding sites in DMSA molecule.

Key words: 2,3 dimercaptosuccinic acid, D-penicillamine, heavy metals, lead, rabbits

Lashev, L. and A. Haritova, 2003. Pharmacokinetics of colistin in broiler chickens. Bulg. J. Vet. Med., 6, No 1, 21-26.

Studies upon the pharmacokinetics of colistin sulfate following single intravenous, single and repeated oral administration (via drinking water) were performed. After i.v. administration, colistin exhibited a two-compartment model of distribution and elimination. The Vdarea was 0.408 l/kg and the biological half-life - 2.19 h. The single oral application at a dose of 50 mg/kg resulted in a weak absorption by the alimentrary tract of broiler chickens (bioavailability of 4.93%) and in blood serum concentrations over 1.0 mg/ml for 6 h. During the treatment via drinking water at a dose of 50 mg/L for 5 days, serum colistin concentrations were higher than  0.7 mg/mL.

Key words: chickens, colistin, pharmacokinetics

Borissov, I., S. Tsanova, I. Panchev, Ph. Stanchev, K. Rachkova and M. Koleva, 2003. Efficacy of the preparation Dentisept in dogs with gingivites, Bulg. J. Vet. Med., 6, No 1, 27-33.

The actuality of dental diseases in pets is a prerequisite for the creation and evaluation of oral antibacterial and deodorizing medications, intended for both prophylaxis and therapy.

The aim of the present study was the evaluation of the antibacterial and antiinflammatory effect of the preparation Dentisept (Primavet, Sofia) in dogs with different forms of gingivites, when applied independently or in combination with other antibacterial preparations.

It was observed that the commonest microbial agents isolated from the buccal cavity of dogs with various dental diseases (dental tartar, gingivites, paradonthopathies etc.) were Gram-positive cocci (staphylococci and streptococci). Their sensitivity to Dentisept was determined on solid nutrient media.

The therapeutical efficacy of Dentisept was assessed via the antibacterial effect, evaluation of salivary pH and the depth of the gingival pocket. It was concluded that Dentisept had an antibacterial and anti-inflammatory effect.

Key words: antibacterial therapy, Dentisept, gingivites, veterinary dentistry

Kirkova, Z., 2003. Studies on the life cycle of Trichuris vulpis. Bulg. J. Vet. Med., 6, No 1, 35-42.

The present studies followed out the dynamics of the entire life cycle of T. vulpis.

The development of Trichuris vulpis eggs to the infective stage was studied in laboratory conditions under various temperatures. It was found out that infective larvae were formed for 14 days at 37 oC, for 17 days at 30 oC, for 45 days at 20 oC and that no development occurred at 4 oC.

The development of T. vulpis in host's organism until the stage of sexual maturity was followed out in 11 experimentally infected dogs, euthanized 1, 3, 6, 10, 15, 20, 30, 42, 50, 67 and 100 days after the infection. It was observed that following the ingestion of parasite's eggs, the larvae hatched in hosts's small intestines and migrated into the mucosa where they developed for 10-15 days. Afterwards thay fell into the intestinal lumen and penetrated caecal and colonic mucosa, where the stage of sexual maturity was reached. The duration of the prepatent period was 112 days while that of the patent one - more than an year.

Key words: dogs, life cycle, Trichuris vulpis